News & Events

Proteomics and Metabolomics Data Analysis Symposium

25/05/2022

Proteomics and Metabolomics Victoria will be hosting a Data analysis Symposium at the Bio21 Institute auditorium on Thursday 8th August from 2:00-3:30pm.

This free event, supported by Bruker, is a great chance to hear from a stellar line up of ECRs and MCRs involved in data analysis from across the fields of proteomics and metabolomics research. These include:

Dr. Anup Shah (Monash University)- Analyze and visualize label-free quantitative proteomics results through LFQ-Analyst

Dr. Michael Leeming (Unimelb/Bio21 Institute)- Kinome – A knowledge-based approach to interpreting high-throughput phospho-proteomics data

Dr. Corey Giles (Baker Heart and Diabetes Institute)- Recent developments in a framework for untargeted lipidomics

Dr. Adam Rainczuk (Applications Scientist, Bruker)- An overview of Metaboscape software for processing and interpreting metabolomics data

Following the Symposium, join us for food, drinks, networking and the PMV AGM at The Castle Hotel, North Melbourne (5 min walk from Bio21 Institute). The AGM is normally held each year to elect office bearers and to make plans for the year ahead, including social events, proteomics/ metabolomics training workshops and annual research symposiums.

The following positions are available for election:

  • Metabolomics President
  • Proteomics president
  • Treasurer
  • Secretary
  • Education Officer
  • Social representative
  • Industry Representative

These positions are open to enthusiastic individuals in the field who are interested in bringing new energy and ideas to the roles. These would be ideal positions for junior postdoctoral researchers looking to improve their scientific networks and to broaden their communication skills.

Those wish to nominate for any of the above positions or learn more about the roles should contact PMV with their expression of interest prior to attending the AGM.

We encourage all current and new PMV members to attend this AGM and be an active part of our local research community.

Please RSVP for attendance at each event separately on Eventbrite to allow for adequate catering at the AGM.

Please direct any enquiries to: proteomics@pmv.org.au

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Alternatives for candesartan [24], but the data are not available. Another alternative for coenzyme Q 10, is tretinoin, which used more frequently in hair loss treatment. In a study of 50 healthy young volunteers with acne, 10 patients (35%) experienced mild or moderately severe hair loss while the 10 control subjects had no changes (28%) in either condition [25]. a similar trial, 10 patients (28%) used the combination of 10% tretinoin (a benzyl alcohol) and finasteride (an anilide derivative) for hair loss, while the remaining 35 (52%) did not use either drug at all [26]. However, even though these studies did not find differences in hair growth between coenzyme Q 10 (active form), finasteride or tretinoin, the candesartan vs losartan price use of one drug (coenzyme discount code for pharmacy online 365 Q 10 ) may alter the hair growth of other medications [27]. In another randomized, double-blind, placebo-controlled, clinical study for the treatment of scalp acne in patients, 10-16% of patients treated using the combination of tretinoin (400 IU weekly), finasteride (25 mg weekly) and tretinoin (500 IU experienced moderate to significant hair loss at the time endpoint, and 11% of patients discontinued because the adverse effects [28]. Of 10 patients who showed mild hair loss, tretinoin caused a total of 13% hair loss in one patient (18%), and 15% hair loss in three patients (26%), while the most adverse event that occurred was severe scalp irritation, which caused by the combination of tretinoin and finasteride. Therefore, it can be safely said that coenzyme Q 10 seems to be a safe and reliable drug in the management of scalp acne, and its combination with other treatments (tretinoin and finasteride) seems effective [16]. Other Hair Loss Medications Besides coenzyme Q 10, additional anti-androgenic and some anti-estrogenic medications have also been proposed to treat mild moderate hair loss symptoms. Examples of other anti-androgenic drugs include tamoxifen, dexamethasone (a steroid hormone replacement therapy [29]), and ropinirole (a synthetic analog of androgens called androstenedione that inhibits 5 alpha-reductase activity in the hair follicles [30]). Some cases of scalp hair loss are associated with high-dose progesterone analogs (estrogen-only medication), which might produce increased androgen production that could lead to hair loss [30, 31]. Another interesting example of a drug that modulates the androgen/testosterone axis is finasteride (a derivative of tretinoin), used for treating advanced prostate cancer. Finasteride prevents androgen production and inhibits both the male female steroid hormones. Finasteride's effects on hair growth are very controversial, and there is much disagreement in the literature whether it affects adult human hair follicles. However, preliminary data of a Phase III trial in men indicate that finasteride's effects on scalp hair gain were not altered by age [32]. There are some other options for the treatment of hair decline as described above. Among them is nafarelin, which approved in the USA and Europe under trade name Provigil [1]. Other alternatives are rivaroxaban (an anticoagulant commonly used to treat blood clots), atorvastatin (a statin), and rifampin; however, they also have the disadvantage that they may not always produce effective hair growth with a minimum of side effects [1, 16, 33]. The choice for hair loss is therefore strongly dependent on the patient's preference toward drugs versus herbal treatments. Hair loss during puberty Hair loss in adults often occurs males with precocious puberty (before the age of 12-13 years), though it has been reported that in adults, hair loss occurs both sexes with precocious puberty [34, 35]. A study of 1,049 Caucasian males who underwent pubertal evaluation found that 17.2% had at least minimal hair loss [36]. Prognosis after treatment with hair growth regimens Hair loss Trimethoprim online order is associated with increased physical and social burden a low quality of life. Although most studies have showed benefits to hair regrowth by topical regimens and finasteride, hair loss in individuals who did not respond to oral treatment, is the most frequent complication of finasteride therapy. In a study of 25 patients treated by oral and topical finasteride plus atorvastatin in the treatment of scalp hair loss, at least a small positive impact on facial hair growth was seen, compared with patients no or minimal scalp hair loss (22 [58%] vs 25 [71%]; P = 0.001).

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Proteomics and Metabolomics Victoria will be hosting a Data analysis Symposium at the Bio21 Institute auditorium on Thursday 8th August from 2:00-3:30pm. This free event, supported by Bruker, is a great chance to hear from a stellar line up of ECRs and MCRs involved in data analysis from across the fields of proteomics and metabolomics research. These […]

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